Teaching Regional Anesthesia to Nurse Anesthesia Students

Teaching regional anesthesia to students who have no experience is a difficult task because there is no common frame of reference, and there are many variables to the provision of this specialized care. The purpose of this independent study was to review three of the most commonly performed blocks then prepare and deliver lessons to nurse anesthesia students which will promote their confidence and competency as anesthesia providers The method used was a review of literature utilizing PubMed, Cl NAHL, and SCOPUS databases. Current thought on preparing students for learning and performing regional methods was organized according to Malcolm Knowles\u27 Adult Learning Theory and Andragogical Model. The principles of regional anesthesia were presented in lecture and power point format, accompanied by video review of anatomy, and then reviewed with demonstration in human anatomy lab on cadavers. The students participated in the demonstration by applying the regional principles on the cadavers to assimilate learned theory and grow in practical applicatio

Homicide and Associated Steroid Acute Psychosis: A Case Report

We report the case of an old man treated with methylprednisolone for chronic lymphoid leukemia. After two months of treatment, he declared an acute steroid psychosis and beat his wife to death. Steroids were stopped and the psychotic symptoms subsided, but his condition declined very quickly. The clinical course was complicated by a major depressive disorder with suicidal ideas, due to the steroid stoppage, the leukemia progressed, and by a sudden onset of a fatal pulmonary embolism. This clinical case highlights the importance of early detection of steroid psychosis and proposes, should treatment not be stopped, a strategy of dose reduction combined with a mood stabilizer or antipsychotic treatment. In addition have been revised the risks of the adverse psychiatric effects of steroids

Comparison of biochemical activities between high and low lipid-producing strains of Mucor circinelloides: An explanation for the high oleaginicity of strain WJ11

© 2015 Tang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The oleaginous fungus, Mucor circinelloides, is one of few fungi that produce high amounts of γ-linolenic acid (GLA); however, it usually only produces +:isocitrate dehydrogenase and NADP NADP+:isocitrate dehydrogenase, however, were 43% and 54%, respectively, lower in WJ11 than in CBS 277.49 and may retard the tricarboxylic acid cycle and thereby provide more substrate for ATP:citrate lyase (ACL) to produce acetyl-CoA. Also, the activities of ACL and fatty acid synthase in the high lipid-producing strain, WJ11, were 25% and 56%, respectively, greater than in strain CBS 277.49. These enzymes may therefore cooperatively regulate the fatty acid biosynthesis in these two strains.Peer Reviewe

Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease

Transcriptomics in Parkinson’s disease (PD) offers new insights into the molecular mechanism of PD pathogenesis. Several pathways, such as inflammation and protein degradation, have been identified by differential gene expression analysis. Our aim was to identify gene expression differences underlying the disease etiology and the discovery of pre-symptomatic risk biomarkers for PD from a multicenter study in the context of the PROPAG-AGEING project. We performed RNA sequencing from 47 patients with de novo PD, 10 centenarians, and 65 healthy controls. Using identified differentially expressed genes, functional annotations were assigned using gene ontology to unveil significant enriched biological processes. The expression of 16 selected genes was validated using OpenArray® assays and samples from independent cohorts of 201 patients with advanced PD, 340 healthy siblings of PD patients, and 177 healthy controls. Differential gene expression analysis identified higher FCGBP expression in patients with de novo PD compared with healthy controls and compared with centenarians. Furthermore, FCGBP showed no differences in terms of population origin or aging process. The increased FCGBP expression was validated in patients with advanced PD and their siblings. Thus, we provided evidence for an upregulation of FCGBP mRNA levels not only in patients with PD but also in individuals at putative higher risk of PD, suggesting that it could be important in gut–brain PD interaction, mediating the connection between microbiota and intestinal inflammatory processes, as well as neuroinflammation and neurodegeneration

El derecho del paciente a decidir sobre su tratamiento: caso clínico de optimización de la farmacoterapia

El intercambio de conocimientos y experiencias entre el farmacéutico y el paciente es parte fundamental en la práctica asistencial de la Optimización de la farmacoterapia, para que así el paciente pueda obtener los mejores resultados de sus medicamentos

El derecho del paciente a decidir sobre su tratamiento: caso clínico de optimización de la farmacoterapia

El intercambio de conocimientos y experiencias entre el farmacéutico y el paciente es parte fundamental en la práctica asistencial de la Optimización de la farmacoterapia, para que así el paciente pueda obtener los mejores resultados de sus medicamentos

Photonic crystal spatial filtering in broad aperture diode laser

Broad aperture semiconductor lasers usually suffer from low spatial quality of the emitted beams. Due to the highly compact character of such lasers, the use of conventional intracavity spatial filters is problematic. We demonstrate that extremely compact photonic crystal spatial filters, incorporated into a laser resonator, can improve the beam spatial quality and, correspondingly, increase the brightness of the emitted radiation. We report the decrease in the M2 value from 47 down to 28 due to photonic crystal spatial intracavity filtering and the increase in the brightness by a factor of 1.5, giving a proof of principle of intracavity photonic crystal spatial filtering in broad area semiconductor lasers.Peer ReviewedPostprint (published version

Punto de partida de los farmacéuticos de la provincia de Alicante en la carrera profesional en farmacia comunitaria según la propuesta de la SEFAC

Objetivo: Valorar la experiencia, los conocimientos y las habilidades de los farmacéuticos de la provincia de Alicante para conocer el punto de partida de cara a una futura implantación del modelo de carrera profesional propuesto por la Sociedad Española de Farmacia Comunitaria (SEFAC). Métodos: Se ha realizado un estudio descriptivo de la información obtenida de currículum vítae (CV) válidos, durante los meses de abril a septiembre del año 2011. Para el estudio se ha elaborado un cuestionario en la plataforma on line GOOGLE DOCS, con el fin de recoger de manera sencilla las puntuaciones de los farmacéuticos al valorar sus CV según el baremo propuesto por la SEFAC. El enlace del cuestionario para la recogida de datos se mandó por correo electrónico desde el Colegio Oficial de Farmacéuticos de Alicante, en 2 veces separadas en el tiempo, y así se pudo disponer de su base de datos y llegar a todos los colegiados de la provincia. También se han enviado más de 200 correos personalizados. Resultados: De 2.081 colegiados (en la fecha de la encuesta), ejercen en oficina de farmacia (OF) 1.563; se han recogido 64 CV válidos (un 3,75% del total y un 4,09% entre ejercientes en OF), lo que puede indicar el bajo interés por la propuesta. Un 90,60% de los participantes tiene el nivel 1 (n= 58), un 6,25% el nivel 2 (n= 4), un 1,57% el nivel 3 (n= 1) y un 1,57% el nivel 4 (n= 1). Conclusiones: El nivel de partida es bajo: 9 de cada 10 participantes tienen el nivel básico. Todos los que superan el nivel 1 son titulares. Las mayores carencias en cuanto a méritos se observan en el apartado de investigación; al no superar los mínimos, muchos participantes con una buena puntuación global no pueden pasar a un nivel superior. Llama la atención la baja participación de los farmacéuticos ante la propuesta de cambio hacia un modelo que refuerza el papel asistencial del farmacéutico comunitario, lo que podría ser consecuencia de la falta de reconocimiento de la labor del farmacéutico por parte de las instituciones sanitarias, así como de la formación académica adquirida en las universidades